Protein Info for BWI76_RS11200 in Klebsiella michiganensis M5al

Annotation: transpeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01476: LysM" amino acids 53 to 89 (37 residues), 23.8 bits, see alignment 5.3e-09 PF03734: YkuD" amino acids 102 to 238 (137 residues), 78.2 bits, see alignment E=1.5e-25 PF17969: Ldt_C" amino acids 242 to 308 (67 residues), 85 bits, see alignment E=7.2e-28

Best Hits

Swiss-Prot: 82% identical to YCFS_ECOLI: Probable L,D-transpeptidase YcfS (ycfS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 86% identity to kpu:KP1_2105)

MetaCyc: 82% identical to L,D-transpeptidase LdtC (Escherichia coli K-12 substr. MG1655)
RXN0-5401

Predicted SEED Role

"L,D-transpeptidase YcfS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2E6 at UniProt or InterPro

Protein Sequence (319 amino acids)

>BWI76_RS11200 transpeptidase (Klebsiella michiganensis M5al)
MKSFSRISLWLGMIAIATALALPARANTWPLPPPGSRLVGQNQFHVVENNGGSLEAIAKK
YNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPREGLVLNLAELRLYYYPPGRSE
VTVYPIGIGQLGGDTITPTMVTTVSDKRANPTWTPTANIRARYKAMGIDLPAVMPAGPDN
PMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCIRLRDDDIKALYNEITPGTKVTIIN
TPIKVSVEPNGARLVEVHQPLSKHIDDDPQTLPIVLNDIMQAFKQAQLTDTEVMERAMTL
RSGMPIDVTRHHRVTEQSL