Protein Info for BWI76_RS10860 in Klebsiella michiganensis M5al

Annotation: ACR family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1024 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 339 to 361 (23 residues), see Phobius details amino acids 368 to 390 (23 residues), see Phobius details amino acids 396 to 419 (24 residues), see Phobius details amino acids 439 to 459 (21 residues), see Phobius details amino acids 471 to 497 (27 residues), see Phobius details amino acids 528 to 548 (21 residues), see Phobius details amino acids 861 to 880 (20 residues), see Phobius details amino acids 887 to 905 (19 residues), see Phobius details amino acids 911 to 934 (24 residues), see Phobius details amino acids 962 to 981 (20 residues), see Phobius details amino acids 987 to 1012 (26 residues), see Phobius details PF00873: ACR_tran" amino acids 14 to 1010 (997 residues), 517.2 bits, see alignment E=4e-159

Best Hits

KEGG orthology group: None (inferred from 82% identity to enc:ECL_02244)

Predicted SEED Role

"RND efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B207 at UniProt or InterPro

Protein Sequence (1024 amino acids)

>BWI76_RS10860 ACR family transporter (Klebsiella michiganensis M5al)
MKKAPSKNTFNLSAWALENPQMVSFFMLLMMVIGSLSYTLLPRNEDPAFTIKTAVVSAQW
PGASVTDTTHLVTDVLEKKLQETPWLDYIESETRAGQTVIYINLRDDTPAQKVPAIWYQI
RKKMQDIAPSLPEGAQGPSVNDEFDDTYGTIYAFIPDGYTLREVRQQVETIRRELMSVPD
IGKTVLLGEQQEQIAIAFSPARLAGMGLSIQQVTDALRAQNAVVPAGVLRTGQEKMTINV
SGALRSEESLRAVTLRINDRYLPLTDIATIERRAAEPPSAAYRVNGRPAVGLAISMAPTG
NMLRFGATLNYRMSAIGAGLPHGIEMVKVADQSAVVSGAVSGFVRVLVEAVLIVLAVSFV
SLGLRAGLVVAAAIPLVLAMTFAGMMLAGIGLQRISLGALIIALGLLVDDAMIAVETMVS
RLEAGDTRRRAATYAFKTTAFPMLTGTLVMIAGFIPVGFASSSAGEYCFSLFAVVLMALL
SSWIVAILFSPLTGAWLLPEKLKHHAAGPGRMARGYGRLLRTALRHRLATLGIALAVLGL
SVYGTTFMQGEFFPSSDRPELLVSLTLLANASQSATEKQTERLERALAGNRNIDHYSTYV
GSGAIRFYLPMDVLLDNENTAQLVVVAKDLAARDRLREQLNTLLSAQFSDLTSRVSPLEL
GPPVGWPIKYRVSGPDYLKVREYAGRLAEAIGRSPLTREVNQTAGEPERTLVLQVNQTAA
RAAGVSSQSLAQTLNTVWSGTTVTSIRDDDRLVDVVLRANDSERLNLATLSSLTVEGRDG
QKISLGAVATPVWGVDDPVLWRRQRLPFITVQTDLAPGMRAEGVSDGLRPTVDKLRAGLP
SGYSIVEGGVVAESEKGNSSVFDILPVTLGVMLLLLMLQLRRYSRMLLALFMAPFGLPGI
VMAMLPSDTPMGFVALLGAIALAGMIIRNAVILISEVDNNLAQGMESDAAIIAAAEHRAR
PIFLTACAAILGMIPISHQVFWGPMAYAIIGGLIVATLVTLTVLPASFSMLLGMGRYWKR
RHAA