Protein Info for BWI76_RS09985 in Klebsiella michiganensis M5al

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 transmembrane" amino acids 15 to 34 (20 residues), see Phobius details amino acids 40 to 57 (18 residues), see Phobius details amino acids 64 to 81 (18 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 389 to 408 (20 residues), see Phobius details amino acids 415 to 431 (17 residues), see Phobius details amino acids 438 to 458 (21 residues), see Phobius details amino acids 464 to 480 (17 residues), see Phobius details amino acids 487 to 503 (17 residues), see Phobius details amino acids 509 to 510 (2 residues), see Phobius details amino acids 512 to 531 (20 residues), see Phobius details TIGR01667: integral membrane protein, YccS/YhfK family" amino acids 8 to 705 (698 residues), 1033.3 bits, see alignment E=0 TIGR01666: TIGR01666 family membrane protein" amino acids 8 to 705 (698 residues), 1125.1 bits, see alignment E=0 PF12805: FUSC-like" amino acids 66 to 345 (280 residues), 360.5 bits, see alignment E=1.1e-111 PF13515: FUSC_2" amino acids 405 to 525 (121 residues), 99.9 bits, see alignment E=2.4e-32 PF04632: FUSC" amino acids 409 to 693 (285 residues), 34.6 bits, see alignment E=1.9e-12

Best Hits

Swiss-Prot: 82% identical to YCCS_ECOLI: Inner membrane protein YccS (yccS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 91% identity to eae:EAE_15365)

Predicted SEED Role

"Putative efflux (PET) family inner membrane protein YccS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B1I7 at UniProt or InterPro

Protein Sequence (711 amino acids)

>BWI76_RS09985 membrane protein (Klebsiella michiganensis M5al)
MLTPLLRRYTRNSAWLYNIRIFIALCGTTAFPWWLGEVKLTIPLTLGVVAAALTDLDDRL
TGRLRNLAITLVCFFIASASVELLFPWPWLFAAGLTVSTIGFILLGGLGQRYATIAFGAL
LIAIYTMLGVTLYSHWYLQPLFLLAGAVWYNLLTLAGHLIFPIRPLQDNLARSYEQLAHY
LELKSRLFDPDIEDESQAPLYDLAIANGQLVATLNQTKVSLLTRLRGDRGQRGTRRTLQY
YFVAQDIHERASSSHIQYQTLRDRFRYSDVMFRFQRMLSMQAQACQKLSRAILLREPYLH
DTHFERAFMHLDAALDRVKASGAPAEQIKALGFLLNNLRAIDAQLATIESVQTTAQFSNN
TENLLADDQPGGFGDVWLRLRSNMSPESALFRHAVRMSLVLCAGYAFIQLTGLNHGYWIL
LTSLFVCQPNYNATRHRLALRIIGTLIGVAIGLPVLLLVPSVEGQLFLIVLTGVLFFAFR
NVQYAHATMFITLLVLLCFNLLGEGFEVALPRIFDTLIGCAIAWAAVSFIWPDWKFRNLP
RVLEQAINANCRYLDAILEQYHQGRDNRLAYRIARRAAHNRDGELASVVSNLSTEPRAGS
QIRETAFRLLCLNHTFTSYISALGAHREKLTTPDILALLDDAVCYVDDALHHSPADEQRV
QQALANLQTRIQHLDPRAESKEPLVLQQIGLLLALLPEICRLQRQVEIQPE