Protein Info for BWI76_RS09695 in Klebsiella michiganensis M5al

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 25 to 28 (4 residues), see Phobius details amino acids 43 to 65 (23 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 102 to 120 (19 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 204 to 225 (22 residues), see Phobius details amino acids 237 to 255 (19 residues), see Phobius details amino acids 266 to 284 (19 residues), see Phobius details amino acids 290 to 311 (22 residues), see Phobius details amino acids 323 to 345 (23 residues), see Phobius details amino acids 351 to 369 (19 residues), see Phobius details PF07690: MFS_1" amino acids 11 to 192 (182 residues), 51.6 bits, see alignment E=1.1e-17 amino acids 210 to 370 (161 residues), 57.1 bits, see alignment E=2.2e-19 PF06779: MFS_4" amino acids 28 to 362 (335 residues), 34.2 bits, see alignment E=2.9e-12 PF00083: Sugar_tr" amino acids 39 to 178 (140 residues), 28.8 bits, see alignment E=9.1e-11

Best Hits

Swiss-Prot: 86% identical to Y1421_ENT38: Uncharacterized MFS-type transporter Ent638_1421 (Ent638_1421) from Enterobacter sp. (strain 638)

KEGG orthology group: K08219, MFS transporter, UMF2 family, putative MFS family transporter protein (inferred from 94% identity to kva:Kvar_3447)

Predicted SEED Role

"Hypothetical MFS-type transporter protein YcaD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B1S7 at UniProt or InterPro

Protein Sequence (382 amino acids)

>BWI76_RS09695 MFS transporter (Klebsiella michiganensis M5al)
MTIYTRPVQMLLCGLLLLTLAIAVLNTLVPLWLAHENMPTWQVGMVGSSYFTGNLVGTLL
AGWVIKRLGFNRSYYLASIIFAVGCVGLGITLGFWSWFSWRFIAGVGCAMIWVVVESALV
CSGTSRSRGRLLAAYMMIYYVGTVLGQLMVSKLPTDLMSVLPWVTALALAAILPLLFARV
ATRGDEPHEPARIWPMLRLRQARHGVNGCIISGIVLGSLYGLMPLWLNHQGVSDSGIGFW
MAVMVSAGIVGQWPIGRLADRYGRLLVLRVQVFVVILGCLAMLSQAAMAPALFVLGASGF
TLYPVAMAWACEKVERHQLVAMNQALLLSYTVGSLLGPTLTAMLMQNFSDNLLFIMIASV
SFIYLLTLLRKAGHHPTPVAHA