Protein Info for BWI76_RS08235 in Klebsiella michiganensis M5al

Annotation: chitoporin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF03573: OprD" amino acids 33 to 432 (400 residues), 88.8 bits, see alignment E=2e-29

Best Hits

Swiss-Prot: 88% identical to CHIP_ECOLI: Chitoporin (chiP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to kva:Kvar_3671)

MetaCyc: 88% identical to chitooligosaccharide outer membrane channel (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-481

Predicted SEED Role

"N-acetylglucosamine-regulated outer membrane porin" in subsystem Chitin and N-acetylglucosamine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B0T5 at UniProt or InterPro

Protein Sequence (467 amino acids)

>BWI76_RS08235 chitoporin (Klebsiella michiganensis M5al)
MRTFSGKRSTLALAIAGVTALSGFAMVPDAKAEGFIDDSTLTGGIYYWQRERDRKDVTDG
DKYKTNLSHSTWNANLDFQSGYAADMFGIDVAAFTAIEMGESSESGHPNEIAFSSRNKGY
DEDYSGDKSGISLYKAAAKFKFGPAWARAGYIQPTGQTLLAPHWSFMPGTYQGAEAGANF
DYGDAGALSFSYMWTNEYKAPWHIEMDEFYQNDKKTKVDYLHSLGAKYDFKNDLVLEAAF
GQAQGYIDQYFAKASYKFDVAGTPLTTSYQFYGTRDKVSNGGANDIYDGTAWLQALTFGY
KVADVLDLRLEGTWVKADGQQGYFLQRMTPTYASSNGRLDIWWDNRSDFNANGEKAVFFG
AMYDMKNWNMPGWAFGASYVYAWDAKPGRMSSPDAYYNPDKRLEESAYSLDAMYTVQEGR
AKGTLFKLHFTQYDNHSDIPSWSGGYGNIFQDERDVKFMVIAPFTIF