Protein Info for BWI76_RS08105 in Klebsiella michiganensis M5al

Annotation: glutamate/aspartate ABC transporter permease GltJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 transmembrane" amino acids 28 to 53 (26 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 182 to 196 (15 residues), see Phobius details amino acids 211 to 233 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 23 to 132 (110 residues), 56.5 bits, see alignment E=1.6e-19 PF00528: BPD_transp_1" amino acids 46 to 238 (193 residues), 94.4 bits, see alignment E=3.6e-31

Best Hits

Swiss-Prot: 90% identical to GLTJ_ECOL6: Glutamate/aspartate import permease protein GltJ (gltJ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K10003, glutamate/aspartate transport system permease protein (inferred from 96% identity to kpe:KPK_3893)

MetaCyc: 90% identical to glutamate/aspartate ABC transporter membrane subunit GltJ (Escherichia coli K-12 substr. MG1655)
ABC-13-RXN [EC: 7.4.2.1]; 7.4.2.1 [EC: 7.4.2.1]

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B0N3 at UniProt or InterPro

Protein Sequence (246 amino acids)

>BWI76_RS08105 glutamate/aspartate ABC transporter permease GltJ (Klebsiella michiganensis M5al)
MSIDWNWGIFLQQAPFGNTTYLGWLWSGFQVTVTLSVTAWIIAFFVGSLFGILRTVPNRL
LSTIGTCYVELFRNVPLIVQFFTWYLVVPELLPENIGMWFKSELDPNIQFFVSSMLCLGL
FTAARVCEQVRSGIQSLPRGQKNAGLAMGLTLPQTYRYVLLPNAYRVIVPPMTSEMMNLV
KNSAIASTIGLADMAAQAGKLLDYSAHAWESFTAITLAYVFINAVIMLIMYVVERKVRLP
GNMGGK