Protein Info for BWI76_RS07600 in Klebsiella michiganensis M5al
Annotation: aspartate aminotransferase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 96% identity to kva:Kvar_3796)MetaCyc: 100% identical to taurine:2-oxoglutarate aminotransferase (Klebsiella oxytoca TauN1)
Taurine--2-oxoglutarate transaminase. [EC: 2.6.1.55]
Predicted SEED Role
"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)
MetaCyc Pathways
- biotin biosynthesis I (15/15 steps found)
- biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)
- taurine degradation III (1/1 steps found)
- superpathway of taurine degradation (3/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.62
Use Curated BLAST to search for 2.6.1.55 or 2.6.1.62
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B0J1 at UniProt or InterPro
Protein Sequence (445 amino acids)
>BWI76_RS07600 aspartate aminotransferase family protein (Klebsiella michiganensis M5al) MKLALQNEVAISNDEVRQLDRAYVFHSWSMQGNLHPLVIAGAKGCELWDYEGNTYLDFSS QLVNVNIGYQHPRVLAAMKAQLEALVTIAPATANLARGEAAKRIVELAPEGFSKVFFTNA GADANENAIRMARLYTGRDKVLSAYRSYHGNTGSAIAATGDWRRVPNEYSRGHVHFFNPY LYRSEFNATTEEEECQRALAHLRRMIECEGPNAIAAILLESIPGTAGILVPPEGYMQGVR ALADEFGIILILDEVMAGFGRTGSWFAFEQDGVVPDLVTFAKGVNAGYVPAGGVLISEPI ARYFDDHFFAGGLTYSGHPLAMAAIVATIDAMKEEKVVENAATIGNEVLRPGLEALAEKH AIIGNVRGRGLFQALELVSSREHKTPLGAADMAAIKGALTEAGLLAFVVENRIHVVPPCT ISAEQVAKGLAIFDAVFARFASLAK