Protein Info for BWI76_RS07230 in Klebsiella michiganensis M5al

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF00356: LacI" amino acids 9 to 46 (38 residues), 35.6 bits, see alignment 9.7e-13 PF13407: Peripla_BP_4" amino acids 63 to 315 (253 residues), 120 bits, see alignment E=2e-38 PF00532: Peripla_BP_1" amino acids 65 to 245 (181 residues), 25.4 bits, see alignment E=1.5e-09

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 75% identity to kpe:KPK_4080)

Predicted SEED Role

"FIG00731626: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B056 at UniProt or InterPro

Protein Sequence (339 amino acids)

>BWI76_RS07230 transcriptional regulator (Klebsiella michiganensis M5al)
MKSMSLEALAKRIGVGVATVDRVLNERGGVSPETTRKVLQAAREAGLKRILPEERRLPWQ
IEVFLSGNDSRFFTRLTQDFADVADSLGYRRLTLHRTLVAESAPEKLAKSIIRSSKKRHA
LIVFGNEHPLVYEALRQCREANVPVITLVTDLPGAQRLCHVGIDQQQAGRTAGRMMGLMA
HRPGEVLMLSGRQDFSAHRLRIQGFREVITQRFPHLQLGEVLAGEDNRQRIDRLLEEALR
RNRDVVGIYNTGLGNTQVAQALARHRRYGECCWITHERYRTTREQLAQGGMALTIDQHAH
QHARLAVELALRHLETGYQPHLFSDGKVEFILYSAENVD