Protein Info for BWI76_RS07010 in Klebsiella michiganensis M5al

Annotation: allantoin permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 transmembrane" amino acids 34 to 82 (49 residues), see Phobius details amino acids 91 to 105 (15 residues), see Phobius details amino acids 115 to 139 (25 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 187 to 212 (26 residues), see Phobius details amino acids 226 to 245 (20 residues), see Phobius details amino acids 266 to 288 (23 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 373 to 397 (25 residues), see Phobius details amino acids 421 to 443 (23 residues), see Phobius details amino acids 451 to 468 (18 residues), see Phobius details TIGR00800: NCS1 nucleoside transporter family" amino acids 15 to 455 (441 residues), 432.5 bits, see alignment E=8.8e-134 PF02133: Transp_cyt_pur" amino acids 22 to 457 (436 residues), 455.2 bits, see alignment E=1.2e-140

Best Hits

Swiss-Prot: 91% identical to ALLP_ECOLI: Putative allantoin permease (ybbW) from Escherichia coli (strain K12)

KEGG orthology group: K10975, allantoin permease (inferred from 95% identity to kpu:KP1_1365)

MetaCyc: 91% identical to allantoin transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-444

Predicted SEED Role

"Allantoin permease" in subsystem Allantoin Utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AZS4 at UniProt or InterPro

Protein Sequence (484 amino acids)

>BWI76_RS07010 allantoin permease (Klebsiella michiganensis M5al)
MEQAQDLYKSRGYSDDLLPKIESQRNWKTFNYFTLWMGSVHNVPNYVMVGGFFILGLSTF
SIMMAIILSAFIIAAVMVFNGAAGSKYGVPFAMILRASYGVRGALLPGLLRGGIAAIMWF
GLQCYAGSLAFLILLGKLWPAFLTLGGDFKLLGLSLPGLIAFLVFWLINVGIGFGGGKVL
NKFTAILNPCIYVVFGGMAIWAISLVGIGPILDYLPTGVEKAEHSGFLFLVVINAVVAVW
AAPAVSASDFTQNARSFRDQALGQTLGLVVAYILFAVAGVCIIAGASIHYDMDTWNVLDI
VQKWDSLFASFFAVLVILMTTISTNATGNIIPAGYQIAAIAPTKLTYKNGVLIASIISLL
ICPWKLMENQDSIYLFLDIIGGMLGPVIGVMMAHYFVVMRGQINLDELYTAPGDYKYFDN
GFNVTAFLVTIVAVILSLGGKFIPLLEPFSRVSWFVGVIVAFAAYALLKKRALPNNISHP
DVVS