Protein Info for BWI76_RS06915 in Klebsiella michiganensis M5al

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 31 to 49 (19 residues), see Phobius details amino acids 55 to 74 (20 residues), see Phobius details PF01957: NfeD" amino acids 94 to 148 (55 residues), 51.6 bits, see alignment E=4.4e-18

Best Hits

Swiss-Prot: 73% identical to YBBJ_ECOLI: Inner membrane protein YbbJ (ybbJ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 87% identity to eae:EAE_13060)

Predicted SEED Role

"Putative activity regulator of membrane protease YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AZQ7 at UniProt or InterPro

Protein Sequence (154 amino acids)

>BWI76_RS06915 membrane protein (Klebsiella michiganensis M5al)
MIALILAHPHIFWLSLGGLLLAAEMLGGNGYLLWSGIAGVVTGLLVWMLPLSWEWQGTLF
AVLTLLAAWLWSRWLRNRVKRQKPADAQLNQRGQQLLGRRFTLETALVNGRGHVRVGDSS
WPVIADEDLAAGSKIEVVAVEGITLRVRELPAGR