Protein Info for BWI76_RS06500 in Klebsiella michiganensis M5al

Annotation: muropeptide transporter AmpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 48 to 68 (21 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 144 to 166 (23 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 225 to 250 (26 residues), see Phobius details amino acids 262 to 281 (20 residues), see Phobius details amino acids 289 to 309 (21 residues), see Phobius details amino acids 317 to 342 (26 residues), see Phobius details amino acids 354 to 376 (23 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 424 to 448 (25 residues), see Phobius details amino acids 458 to 484 (27 residues), see Phobius details PF13000: Acatn" amino acids 16 to 164 (149 residues), 42.6 bits, see alignment E=3.1e-15 PF07690: MFS_1" amino acids 17 to 365 (349 residues), 99.3 bits, see alignment E=2.2e-32 amino acids 242 to 483 (242 residues), 40.7 bits, see alignment E=1.5e-14 TIGR00901: AmpG-like permease" amino acids 25 to 363 (339 residues), 411.2 bits, see alignment E=2.2e-127

Best Hits

Swiss-Prot: 85% identical to AMPG_ECOLI: Anhydromuropeptide permease (ampG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 92% identity to eae:EAE_12735)

MetaCyc: 85% identical to muropeptide:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-226; TRANS-RXN0-258

Predicted SEED Role

"AmpG permease"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AZR3 at UniProt or InterPro

Protein Sequence (491 amino acids)

>BWI76_RS06500 muropeptide transporter AmpG (Klebsiella michiganensis M5al)
MSNHYLRIFTQPKSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYV
FKFLWSPLMDRYTPPFLGRRRGWLLATQFLLLIAIAAMGFLEPSTQLRWMAALAVVIAFC
SASQDIVFDAWKTDVLAAEERGTGAAISVLGYRLGMLVSGGLALWLADRWLGWQGMYWLM
AALLIPCIIATLLAPDPSDVIPVPKTLEQAVAAPLRDFFGRNNAWLILLLIVLYKLGDAF
AMSLTTTFLIRGVGFDAGEVGMVNKTLGLFATIVGALYGGVLMQRLTLFRALLIFGVLQG
VSNAGYWLLSITDKHLFSMATAVFFENLCGGMGTAAFVALLMTLCNKSFSATQFALLSAL
SAVGRVYVGPIAGWFVEAHGWPAFYLFSVVAAVPGILLLLICRRTLEHTQRSESFMPRTF
FPQIYGLALMILAVGCLMLAVWLVLLVFNALDYTNFSFLAGLLEIAVLTAVAGILLGAFL
DYLALRKTELI