Protein Info for BWI76_RS05910 in Klebsiella michiganensis M5al

Annotation: phosphonate ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 TIGR02315: phosphonate ABC transporter, ATP-binding protein" amino acids 27 to 273 (247 residues), 292.4 bits, see alignment E=1.3e-91 PF00005: ABC_tran" amino acids 44 to 205 (162 residues), 109.6 bits, see alignment E=1.9e-35

Best Hits

Swiss-Prot: 66% identical to PHNC_YERPE: Phosphonates import ATP-binding protein PhnC (phnC) from Yersinia pestis

KEGG orthology group: None (inferred from 91% identity to eae:EAE_12200)

Predicted SEED Role

"Phosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AZD7 at UniProt or InterPro

Protein Sequence (280 amino acids)

>BWI76_RS05910 phosphonate ABC transporter ATP-binding protein (Klebsiella michiganensis M5al)
MNSSLAAVAETEFQPFTPPYTDRQRKVLSVRNLSKSWNAQQTVLDSISFDLHAGELVGVI
GRSGAGKSTLLHLLNGTHSASGGEILSFPEVGTPQDVSKLSGRALNAWRSRCGMIFQDFC
LVPRLDVLTNVLLGRLSQTSTLKSLFKVFPDADRARAISLLEWMNMLPQALQRAENLSGG
QMQRVAICRALMQNPGILLADEPVASLDPKNTQRIMNVLREISEQGISVMVNLHSVELVR
EYCTRVIGVAKGQISFDDHPTQLNQEILHRLYGDEISQLH