Protein Info for BWI76_RS05720 in Klebsiella michiganensis M5al

Annotation: cation/multidrug efflux pump

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1029 transmembrane" amino acids 19 to 38 (20 residues), see Phobius details amino acids 339 to 357 (19 residues), see Phobius details amino acids 363 to 381 (19 residues), see Phobius details amino acids 393 to 415 (23 residues), see Phobius details amino acids 431 to 454 (24 residues), see Phobius details amino acids 467 to 490 (24 residues), see Phobius details amino acids 524 to 548 (25 residues), see Phobius details amino acids 861 to 879 (19 residues), see Phobius details amino acids 886 to 907 (22 residues), see Phobius details amino acids 913 to 935 (23 residues), see Phobius details amino acids 963 to 983 (21 residues), see Phobius details amino acids 989 to 1012 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 9 to 1011 (1003 residues), 492.1 bits, see alignment E=1.6e-151

Best Hits

KEGG orthology group: None (inferred from 94% identity to ent:Ent638_1874)

Predicted SEED Role

"Cation efflux system protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AZ93 at UniProt or InterPro

Protein Sequence (1029 amino acids)

>BWI76_RS05720 cation/multidrug efflux pump (Klebsiella michiganensis M5al)
MSDGKFNLSALAVRERSITLFLIILITVAGVLSFFELGRAEDPPFTVKQMTIISAWPGAT
AQEMQDQVAEPLEKRMQELKWYDRSETYTRPGLAYTMLSLQDSTPPSQVQEEFYQARKKL
GDEAKNLPAGVIGPMFNDEFSDVTFALFALKAKGEPQRLLVRDAESLRQRLLHVPGVKKV
NIIGEQAERIFVSFSHDRLATLGVSPQDIFSALNSQNVLTPAGSIDTKGPQVFIRLDGAF
DKLEKIRETPIVVQGRTLQLSDVATVERGYEDPATFQNRNQGETALLLGIVMRDGWNGLD
LGKALDAETAKINAGMPLGMTLTKVTDQSVNISSAVDEFMIKFFVALLVVMVVCFVSMGW
RVGVVVAAAVPLTLAIVFVVMEASGKNFDRITLGSLILALGLLVDDAIIAIEMMVVKMEE
GYDRIKASAYAWSHTAAPMLAGTLVTAVGFMPNGFAQSTAGEYTSNMFWIVGIALIASWI
VAVVFTPYLGVKMLPDIKKVEGGHAAIYNTRHYNRFRRLLAWVIARKWIVAGTVIAVFTV
AILGMGLVKKQFFPTSDRPEVLVEVQMPYGTAIEQTNATAAKIEAWLRKQKEAKIVTSYI
GQGAPRFFLAMAPELPDPSFAKIVVLTDNPEAREALKFRLREAVAGGLTPEARVRVTQLV
FGPYSPYPVAYRVMGPDPTTLREIADKVEKVMQASPMMRTVNTDWGPRVPALHFTLNQDR
LQAVGLTSNAAAQQLQFLLSGIPITSVREDIRSVQVMGRAAGDIRLDPAKIAGFTLVGAA
GQRIPLSQIGEIEVQMEEPVMRRRDRIPTITVRGDIAENLQPPDVSTAITKALQPVIDTL
PDGYRIEQAGSIEESGKATKAMVPLFPIMIAMTLLIIILQVRSMAAMVMVFLTAPLGLIG
VVPTLLLFNQPFGINTLVGLIALSGILMRNTLILIGQIHHNEQEGLAPFHAVVEATVQRA
RPVLLTAMAAILAFIPLTHSVFWGTLAYTLIGGTFGGTIITLVFLPAMYAIWFKIRPDTQ
KPAEPQAAV