Protein Info for BWI76_RS04835 in Klebsiella michiganensis M5al
Annotation: type II secretion system protein GspE
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 70% identical to HOFB_ECOLI: Protein transport protein HofB homolog (hofB) from Escherichia coli (strain K12)
KEGG orthology group: K02504, protein transport protein HofB (inferred from 85% identity to kpu:KP1_0930)Predicted SEED Role
"Type IV fimbrial assembly, ATPase PilB" in subsystem Type IV pilus
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285AYJ8 at UniProt or InterPro
Protein Sequence (461 amino acids)
>BWI76_RS04835 type II secretion system protein GspE (Klebsiella michiganensis M5al) MKTEQLIPLCQRYKALLLDSDEHTIAIAVVDAPAPELMEALRFATQKRIDIECWSQDRMD KRLQTPGISTLAPPVEASASVVEQVNNLLEQALRQRASDIHIEPGDDRLRIRLRVDGVLH SLAPLAAELAAPITARLKVLGNLDIAEHRVPQDGQFTLTLSERPISFRIATLPCRGGEKI VLRLLHQVEQALDLEALGLSSQQLAAFRSALNQPQGLMLVTGPTGSGKTVTLYSALQARN RDEVNICSVEDPLEIPIVGMNQTQINPRAGLTFHSVLRALLRQDPDIVMVGEIRDAETAE IAIKAAQTGHLVLSTLHTNSTSETLVRLQQMGVARWMISSALSLVVAQRLVRKLCPHCRR ETGSSADVPHSLWPRALPRWQAPGCQHCYHGYYGRLALFELLPVNTTLRQAITQGLSAGE IESLARESGMMTLFESGCLAVERGMTSLEEVVRVLGIPHGD