Protein Info for BWI76_RS04785 in Klebsiella michiganensis M5al

Annotation: cell division protein FtsZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 TIGR00065: cell division protein FtsZ" amino acids 7 to 338 (332 residues), 470.7 bits, see alignment E=1.8e-145 PF00091: Tubulin" amino acids 13 to 172 (160 residues), 175.3 bits, see alignment E=1.8e-55 PF12327: FtsZ_C" amino acids 221 to 315 (95 residues), 126.7 bits, see alignment E=3.6e-41

Best Hits

Swiss-Prot: 98% identical to FTSZ_ECOL6: Cell division protein FtsZ (ftsZ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03531, cell division protein FtsZ (inferred from 98% identity to eoi:ECO111_0098)

Predicted SEED Role

"Cell division protein FtsZ (EC 3.4.24.-)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AYI8 at UniProt or InterPro

Protein Sequence (383 amino acids)

>BWI76_RS04785 cell division protein FtsZ (Klebsiella michiganensis M5al)
MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQI
GSGITKGLGAGANPEVGRNAADEDREALRAALDGADMVFIAAGMGGGTGTGAAPVVAEVA
KDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLD
AFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAA
EMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDP
DMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMSPLTQEQKPAAKVVND
NTPQAAKEPDYLDIPAFLRKQAD