Protein Info for BWI76_RS04630 in Klebsiella michiganensis M5al

Annotation: sugar efflux transporter SetB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 48 to 70 (23 residues), see Phobius details amino acids 82 to 99 (18 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 140 to 166 (27 residues), see Phobius details amino acids 168 to 168 (1 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 221 to 242 (22 residues), see Phobius details amino acids 255 to 277 (23 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 309 to 331 (23 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 371 to 389 (19 residues), see Phobius details TIGR00899: sugar efflux transporter" amino acids 17 to 393 (377 residues), 541.7 bits, see alignment E=4.7e-167 PF07690: MFS_1" amino acids 19 to 304 (286 residues), 106.5 bits, see alignment E=7.4e-35 amino acids 222 to 387 (166 residues), 59.7 bits, see alignment E=1.2e-20

Best Hits

Swiss-Prot: 85% identical to SETA_ECOLI: Sugar efflux transporter A (setA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to eae:EAE_11135)

MetaCyc: 85% identical to sugar exporter SetA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-82

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AYF9 at UniProt or InterPro

Protein Sequence (394 amino acids)

>BWI76_RS04630 sugar efflux transporter SetB (Klebsiella michiganensis M5al)
MLWLMTMGRRLNGVYAAFMLVAFMMGIAGALQAPTLSLFLSREVGAQPFWVGLFYTVNAI
AGILVSLALAKRSDSRGDRRRLIMFCCLMAVGNALLFAFNRHYLTLITCGVMLASVANAA
MPQLFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLAFMLALNYGFTTMFSIAAGI
FVISLALIAFKLPSVARVEQPSEGAEVLVQAGGWHDKNVRMLFIASTLMWTCNTMYIIDM
PLWISSDLGLPDSLAGILMGTAAGLEIPAMILAGYYVKRWGKRNMMVTAVAAGVLFYIGL
ILFHDRVALLILQLFNAVFIGIVAGIGMLWFQDLMPGRAGAATTLFTNSISTGVILAGVI
QGALSQSYGHASVYWTIAAISLVTLFMTSRVKDI