Protein Info for BWI76_RS04605 in Klebsiella michiganensis M5al

Annotation: thiamine ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01277: thiamine ABC transporter, ATP-binding protein
  • amino acids 2 to 213 (212 residues), 358.6 bits, E=5.4e-112
• PF00005: ABC_tran
  • amino acids 18 to 157 (140 residues), 130.2 bits, E=9e-42
• PF13304: AAA_21
  • amino acids 126 to 190 (65 residues), 29.8 bits, E=6e-11

Best Hits

Swiss-Prot: 78% identical to THIQ_SHIDS: Thiamine import ATP-binding protein ThiQ (thiQ) from Shigella dysenteriae serotype 1 (strain Sd197)

KEGG orthology group: None (inferred from 88% identity to eae:EAE_11110)

MetaCyc: 78% identical to thiamine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-32-RXN [EC: 7.6.2.15]

Predicted SEED Role

"Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ" in subsystem Thiamin biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.15

Sequence Analysis Tools

See A0A285AYL0 at UniProt or InterPro

Protein Sequence (233 amino acids)

>BWI76_RS04605 thiamine ABC transporter ATP-binding protein (Klebsiella michiganensis M5al)
MLKLNDVTWLYQHLPMRFTLAVERGERIAVLGPSGAGKSTLLNLIAGFLPPASGSIDIDG
QPHTHTPPARRPVSMLFQENNLFNHLTIRQNIALGMHPGLKLNAEQTAHLRAIAEQMGID
AMLERLPGELSGGQRQRAALARCLVRKQPVLLLDEPFSALDPALRQEMLALVADVCQQQR
LTLLMVSHSVEDAARIAPRSIVVAEGRIAWDGDTASLLSGNSSASALLGISAK