Protein Info for BWI76_RS04590 in Klebsiella michiganensis M5al
Annotation: ribulokinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 92% identical to ARAB_KLEP3: Ribulokinase (araB) from Klebsiella pneumoniae (strain 342)
KEGG orthology group: K00853, L-ribulokinase [EC: 2.7.1.16] (inferred from 92% identity to kpn:KPN_00062)MetaCyc: 88% identical to ribulokinase (Escherichia coli K-12 substr. MG1655)
Ribulokinase. [EC: 2.7.1.16]
Predicted SEED Role
"Ribulokinase (EC 2.7.1.16)" in subsystem L-Arabinose utilization (EC 2.7.1.16)
MetaCyc Pathways
- L-arabinose degradation I (4/4 steps found)
- D-arabinose degradation I (2/2 steps found)
- ribitol degradation I (2/2 steps found)
- D-arabinose degradation V (1/3 steps found)
- superpathway of pentose and pentitol degradation (21/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.7.1.16
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285AYJ2 at UniProt or InterPro
Protein Sequence (569 amino acids)
>BWI76_RS04590 ribulokinase (Klebsiella michiganensis M5al) MAIAIGLDFGSDSVRALAVECATGEELAASVEWYPRWQEGLFCDGPNNQFRHHPRDYIES MEAALKSVLASLSAEQRAAVVGIGVDSTGSTPAPIDADGNVLALRDEFASNPNAMFVLWK DHTSVEEAEEITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTRQDSAVAEAAASWIEL CDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPAGFFDELDPIINQNLAYPMFS ETWTADVPVGTLTAEWAARLGLPQTVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDI LIADKQSVGERTVKGICGQVDGSVVPDFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQAH PELKEQIKASQKQLLPALTDAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLA TDAPALFGGLIAATAFGARAIMECFTDQGIPVNNVMALGGIARKNPVIMQACCDVLNRPL QIVASDQCCALGAAIFAAVAAGVYRDIPAAQENMASQVESTLQPRPAQAQRFEQLYQRYQ QWSLSAEQRYLPSTAKAETAPQSQAALTH