Protein Info for BWI76_RS04370 in Klebsiella michiganensis M5al
Annotation: FldA family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 69% identical to YBHH_SHIFL: Putative isomerase YbhH (ybhH) from Shigella flexneri
KEGG orthology group: None (inferred from 81% identity to eae:EAE_10880)MetaCyc: 51% identical to 4-oxalomesaconate tautomerase (Pseudomonas putida KT2440)
RXN-9983 [EC: 5.3.2.8]
Predicted SEED Role
No annotation
MetaCyc Pathways
- gallate degradation I (4/4 steps found)
- gallate degradation II (4/5 steps found)
- protocatechuate degradation I (meta-cleavage pathway) (6/8 steps found)
- superpathway of vanillin and vanillate degradation (7/10 steps found)
- methylgallate degradation (4/6 steps found)
- syringate degradation (6/12 steps found)
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.3.2.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285AYH6 at UniProt or InterPro
Protein Sequence (351 amino acids)
>BWI76_RS04370 FldA family protein (Klebsiella michiganensis M5al) MKSIPCVLMRGGTSKGAFLLADDLPKDIQKRDDCLLAIMGSGHELEIDGIGGGSPQTSKV AIISQSLSEEADIDYLFVQVIVNERRVDTTPNCGNMLCAVGGFAIEHGLVEAASPVTRVR IRNVNTNTFIDADVQTPDGKVIYEGDSQIDGVPGRAAPVALTFLNAAGAKSGRLFPTGNR MDVFDDVRVTCIDMAMPMVVIPAQSLGKTGYESASELDRDSGLLKSLESIRIQAGKAMGF GDVTNMVIPKPVLISPALSGGSINVRYFMPHNCHKSLAITGAIGLASACIIPKTIANELT KLSGDGIIKVEHPSGGIEVDLSQTTERPEDIRASVIRTARKILSGTVYIPE