Protein Info for BWI76_RS03550 in Klebsiella michiganensis M5al

Annotation: QacE family quaternary ammonium compound efflux SMR transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 139 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 37 to 54 (18 residues), see Phobius details amino acids 66 to 86 (21 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details PF00893: Multi_Drug_Res" amino acids 8 to 101 (94 residues), 67.5 bits, see alignment E=6.2e-23

Best Hits

KEGG orthology group: None (inferred from 89% identity to eae:EAE_10045)

Predicted SEED Role

"Ethidium bromide-methyl viologen resistance protein EmrE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AY00 at UniProt or InterPro

Protein Sequence (139 amino acids)

>BWI76_RS03550 QacE family quaternary ammonium compound efflux SMR transporter (Klebsiella michiganensis M5al)
MSSKTKCWLWMLLVIVSETSATSTLKMFGSSEGMTKMLLLGLLVLLYCTCYYSLSRAVKD
IPVGLAYATWSGTGILVVSTLGMAFYGQHPDTAAIIGMAVIASGIVIMNLFSKMGSEESE
EAPAQPAAAAASLDKKVAN