Protein Info for BWI76_RS03050 in Klebsiella michiganensis M5al

Annotation: LPS export ABC transporter permease LptF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 16 to 37 (22 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 97 to 120 (24 residues), see Phobius details amino acids 267 to 289 (23 residues), see Phobius details amino acids 296 to 316 (21 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details TIGR04407: LPS export ABC transporter permease LptF" amino acids 2 to 348 (347 residues), 386.6 bits, see alignment E=4.1e-120 PF03739: LptF_LptG" amino acids 5 to 345 (341 residues), 262.2 bits, see alignment E=3.5e-82

Best Hits

Swiss-Prot: 86% identical to LPTF_ECO57: Lipopolysaccharide export system permease protein LptF (lptF) from Escherichia coli O157:H7

KEGG orthology group: K07091, lipopolysaccharide export system permease protein (inferred from 94% identity to kpe:KPK_5001)

MetaCyc: 87% identical to lipopolysaccharide ABC transporter permease (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-51 [EC: 7.5.2.5]

Predicted SEED Role

"FIG000988: Predicted permease"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWW5 at UniProt or InterPro

Protein Sequence (365 amino acids)

>BWI76_RS03050 LPS export ABC transporter permease LptF (Klebsiella michiganensis M5al)
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPTNLVLSLLGLGVPEMA
QLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILALFTGIVAAVNVMWA
GPWSSRHQDEVLAEAKANPGMAALAQGQFQQASDGSAVLFIENVNGNRFSDVFLAQLRPR
GNARPSVVVADTGELSLRKDGSQVVTMNQGTRFEGTAMLRDFRITDFKNYQAIVGHQAVA
SDPNDTEQMDMRTLWRTDTDRARAELHWRFTLVATVFIMALMVVPLSVVNPRQGRVLSML
PAMLLYLVFFLLQTSIKSSGGKGKMDPMIWMWAVNLLYFALAVLLNLWDTVPMRRFRARF
NKGAA