Protein Info for BWI76_RS02900 in Klebsiella michiganensis M5al

Annotation: 6-phosphogluconolactonase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF10282: Lactonase" amino acids 26 to 377 (352 residues), 327.6 bits, see alignment E=1.5e-101

Best Hits

KEGG orthology group: None (inferred from 91% identity to eae:EAE_09650)

Predicted SEED Role

"Putative hemagglutinin-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWV3 at UniProt or InterPro

Protein Sequence (383 amino acids)

>BWI76_RS02900 6-phosphogluconolactonase (Klebsiella michiganensis M5al)
MPTARHLLVASLSLLAAGAAAQTHYAWVGTYNPNGEGLYRFTVDSQTGALRDKALVAKLP
NLAQLAVSADGKTLYAASEVDKGVVQAWRIGSNGELSELNQVASGGAGPVYLSLTPDGRH
LLVANYVSGSIAVLPVKEEGNLGEAVDIHQDQGPAGAERPAAAVEGSFAISDHNGPHAHM
VAADPSGRFVYSTDLGLDRIYQYRLDNASGKLTPNDPPFIDASSPGAGPRHFVFTPQGDG
LWLINEEASTLTFYHLDKQSGLLREGKTVSALPEEYKGTSFAAGLVLSRDGKQLYVANRL
HNSIAHFTVLADGSLSHQEDIWTRGDYPRTLTLDSQEQWLYVMNQRSDNITRFRVAPKDG
RLTFSPDYTPVGGPSQMVISAQP