Protein Info for BWI76_RS02895 in Klebsiella michiganensis M5al

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07071: KDGP_aldolase
  • amino acids 8 to 225 (218 residues), 362.2 bits, E=5.5e-113
• TIGR03581: conserved hypothetical protein EF_0839/AHA_3917
  • amino acids 8 to 243 (236 residues), 405.4 bits, E=4e-126

Best Hits

KEGG orthology group: None (inferred from 93% identity to kpn:KPN_04640)

Predicted SEED Role

"2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) in D-glucosaminate utilization operon" (EC 4.1.2.14)

MetaCyc Pathways

• superpathway of glycolysis and the Entner-Doudoroff pathway (17/17 steps found)
• Entner-Doudoroff pathway I (9/9 steps found)
• superpathway of hexuronide and hexuronate degradation (9/10 steps found)
• 4-deoxy-L-threo-hex-4-enopyranuronate degradation (5/5 steps found)
• D-galacturonate degradation I (5/5 steps found)
• D-fructuronate degradation (4/4 steps found)
• superpathway of β-D-glucuronosides degradation (6/7 steps found)
• Entner-Doudoroff shunt (2/2 steps found)
• D-glucosaminate degradation (2/3 steps found)
• Entner-Doudoroff pathway III (semi-phosphorylative) (6/9 steps found)
• 3,6-anhydro-α-L-galactopyranose degradation (4/7 steps found)
• superpathway of microbial D-galacturonate and D-glucuronate degradation (19/31 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Pentose and glucuronate interconversions
• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 4.1.2.14

Use Curated BLAST to search for 4.1.2.14

Sequence Analysis Tools

See A0A285AWU6 at UniProt or InterPro

Protein Sequence (246 amino acids)

>BWI76_RS02895 hypothetical protein (Klebsiella michiganensis M5al)
MKLTPNFYRDRVCLNVLAGSKDNASEIYEAAEGHVLVGVLSKNYPDVASAVADMREYALR
IDNALSVGLGAGDPNQSAMVSEISRQVQPQHVNQVFTGVATSRALLGQNDTVVNGLVSPT
GTPGMVKISTGPLSSGAPDGIVPLETAIALLKDMGGSSIKYFPMGGLKHRDEFIAVAEAC
ARYDFWLEPTGGIDLENYGEILQIALDAGVSKIIPHIYSSIIDKASGNTRPADVRQLLSI
TKQLVK