Protein Info for BWI76_RS02570 in Klebsiella michiganensis M5al

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 TIGR00738: Rrf2 family protein" amino acids 1 to 128 (128 residues), 125.6 bits, see alignment E=6.1e-41 PF02082: Rrf2" amino acids 3 to 129 (127 residues), 127.1 bits, see alignment E=2.5e-41

Best Hits

Swiss-Prot: 97% identical to NSRR_KLEP3: HTH-type transcriptional repressor NsrR (nsrR) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: None (inferred from 97% identity to eae:EAE_09350)

Predicted SEED Role

"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWR7 at UniProt or InterPro

Protein Sequence (141 amino acids)

>BWI76_RS02570 transcriptional regulator (Klebsiella michiganensis M5al)
MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYGVSRNHMVKIINQLSRVGYVTAVRG
KNGGIRLGKPANMIRVGDVVRDLEPLSLVNCSSEFCHITPACRLKQALAEAAQSFLKELD
NYTLADLVEKNQPLYKLLLVE