Protein Info for BWI76_RS02395 in Klebsiella michiganensis M5al

Annotation: gram-negative pili assembly chaperone protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00345: PapD_N" amino acids 23 to 142 (120 residues), 118.9 bits, see alignment E=1.4e-38

Best Hits

Swiss-Prot: 31% identical to YRAI_ECOLI: Probable fimbrial chaperone YraI (yraI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 59% identity to kpu:KP1_0411)

Predicted SEED Role

"Putative fimbrial chaparone"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (230 amino acids)

>BWI76_RS02395 gram-negative pili assembly chaperone protein (Klebsiella michiganensis M5al)
MFKSLLKIVAVISLSASFVAHSGVVVDSTRHLYKEGTREISANLENKDNIPYLVKSWVEP
REGNATSFFMVTPPLFRLEAKQKNTVRIFPNANIINAPKDRESVYYFNVMSIPPTSDADT
DKNRIQLAVRHRMRLIYRPSSLQDLSINQEAKKLEWRKVNNKITVKNTTPFFIYFKSIKI
NGVELSGFINNIDAFATKEFSLPAGANGSEVEWKIATDNGGTGSAYSVSI