Protein Info for BWI76_RS02390 in Klebsiella michiganensis M5al

Annotation: fimbrial biogenesis outer membrane usher protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 847 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF13954: PapC_N" amino acids 40 to 189 (150 residues), 123.1 bits, see alignment E=1.4e-39 PF00577: Usher" amino acids 203 to 758 (556 residues), 620.8 bits, see alignment E=4e-190 PF13953: PapC_C" amino acids 770 to 833 (64 residues), 60.9 bits, see alignment 1.2e-20

Best Hits

Swiss-Prot: 41% identical to LPFC_SALTY: Outer membrane usher protein LpfC (lpfC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07347, outer membrane usher protein (inferred from 63% identity to kpe:KPK_5130)

Predicted SEED Role

"FIG00731956: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (847 amino acids)

>BWI76_RS02390 fimbrial biogenesis outer membrane usher protein (Klebsiella michiganensis M5al)
MSILIKKRDDVFSSVSRTFFVLVPALALGFSNNTLARDFFDPDFIKSVGQNDPSSIPDLS
LYATKDAQAPGKYRIDVVLNNNLQETTDVRFVEKKDSATGDLKLVPCLSIATLKNYGLRT
EAFPTLKEDADGCTNTNIIPNFKTDFNFNTQQLLISIPQAALSTIAQGFVPPEEYDDGIN
ALLTNYQFSSGKDYEANNEYYNLNLQSGLNIGPWRLRNLSTWNKSAGAKSDWDSVYLYAQ
RSIIPLKSKLVMGESSSLSSIFDSVPFTGVQLATDEDMIPESLRGFAPIVRGIARTNARV
VIKQNGYQIYQAFVAPGAFEITDLYSTGGNGDLYVTVEEADGSRQNFVVPYASLPLMLRE
GQMEYEITSGQYRPYDDNIDEKPFTQATISYGALSNTTFYTGIQAASNYQALAFGVGQNL
GDIGALSADVTEAWSKKKDADKTSGQSWRIRYGKNIIETGTNITVAGYRYSTSGFNTLTD
VMNTYNNRYGGYTSHSIRNRTNITVSQSLGSGLGSLSVSGIFEDYWDSNRHNNSLNVGYN
GGFRRFNYYAGYSYSRYSWSNNGSSRTAEDDHVFTFNITVPLSDWLPKTYATYNVTNSSP
GSTDQYVSLSGTALENDKLDWNVQQGYSNREDASGGVYGNYRGSMGSVNGGYSYSKHSQL
VNYGMSGGALVHADGITLGQEMSETSVLVKAPGLDHVRLENDETVETDYRGYAILPYVTP
YHRTSVTLDSTSLSDNMELPNTTQKVVPTRAAIVRANFEGSIGRRAFLILKRTSGENVPY
GATVTPALDKKAQASIVSDGGMVYMSGLKDTGDVYAQWGTKAGQNCTASYNLADQSANIA
QVSAVCR