Protein Info for BWI76_RS02145 in Klebsiella michiganensis M5al

Annotation: allose kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00480: ROK" amino acids 9 to 299 (291 residues), 271.6 bits, see alignment E=5e-85

Best Hits

Swiss-Prot: 77% identical to ALSK_ECOLI: D-allose kinase (alsK) from Escherichia coli (strain K12)

KEGG orthology group: K00881, allose kinase [EC: 2.7.1.55] (inferred from 78% identity to ecp:ECP_4326)

MetaCyc: 77% identical to D-allose kinase (Escherichia coli K-12 substr. MG1655)
Allose kinase. [EC: 2.7.1.55]

Predicted SEED Role

"D-allose kinase (EC 2.7.1.55)" in subsystem D-allose utilization (EC 2.7.1.55)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWL9 at UniProt or InterPro

Protein Sequence (308 amino acids)

>BWI76_RS02145 allose kinase (Klebsiella michiganensis M5al)
MQKQRNVVAGVDMGATHIRLCLQTAQGEALHCEKRRTADVISADGLVNGIKNLLQQQLTL
HDARCCGLVMGFPALVAKDKRTIISTPNLPLAADDLYNLADRLEAALCCPVEFSRDVNLQ
LSFDVQENGLQEQEVLAAYLGTGMGFAVWLNGGPWTGAHGVAGELGHIPLGDDALTCACG
NPACLETVCSGIALKRWYEQQPRAYELGELFVHAEQEPFVQTLLNHAARAIATSVNLFDP
DAVILGGGVMDMPAFPRDTLIAMVKTYVRRPLPYQAVRFIAASSSAFNGAQGAAALARSR
YLPLPVTV