Protein Info for BWI76_RS01335 in Klebsiella michiganensis M5al
Annotation: DNase TatD
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 82% identical to TATD_KLEP3: 3'-5' ssDNA/RNA exonuclease TatD (tatD) from Klebsiella pneumoniae (strain 342)
KEGG orthology group: None (inferred from 83% identity to eae:EAE_08025)MetaCyc: 73% identical to 3' -> 5' ssDNA/RNA exonuclease TatD (Escherichia coli K-12 substr. MG1655)
3.1.13.-; Exodeoxyribonuclease I. [EC: 3.1.11.1]
Predicted SEED Role
"Deoxyribonuclease TatD" in subsystem Twin-arginine translocation system or YcfH
Isozymes
Compare fitness of predicted isozymes for: 3.1.11.1
Use Curated BLAST to search for 3.1.11.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285AW01 at UniProt or InterPro
Protein Sequence (260 amino acids)
>BWI76_RS01335 DNase TatD (Klebsiella michiganensis M5al) MFDIGVNLTSSQFSRDRDEVVSRARAAGVTGMLLTGTNLHESAQAQQMARRYSGCWSTAG VHPHDSRCWTDSVAAAVYALAREPEVVAVGECGLDFNRNFSTPQEQEAAFSAQLALAAEL SMPVFLHCRDAHERFLALLVPWLDKLPGAVVHCFTGSREEMRECVEHGLFIGITGWVCDE RRGLELRALLADIPADRLLVETDAPYLLPRDMRPKPASRRNEPAYLPHILTSIAGWRGEE AQWLEEITDANVRRLFGVRF