Protein Info for BWI76_RS00660 in Klebsiella michiganensis M5al

Annotation: ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 503 PF00005: ABC_tran" amino acids 23 to 174 (152 residues), 111.2 bits, see alignment E=6.5e-36 amino acids 275 to 427 (153 residues), 82.1 bits, see alignment E=6.1e-27

Best Hits

Swiss-Prot: 60% identical to RBSA_ROSDO: Ribose import ATP-binding protein RbsA (rbsA) from Roseobacter denitrificans (strain ATCC 33942 / OCh 114)

KEGG orthology group: K10562, rhamnose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 94% identity to kpn:KPN_04209)

Predicted SEED Role

"Predicted L-rhamnose ABC transporter, ATP-binding component" in subsystem L-rhamnose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AVM8 at UniProt or InterPro

Protein Sequence (503 amino acids)

>BWI76_RS00660 ABC transporter (Klebsiella michiganensis M5al)
MSASTPLLSLKGITKVFPGVRALENVQLDLWPGKVTALIGENGAGKSTLVKVMTGIYQPE
EGEILYKAIPIQLPNPESAHKVGITAIHQETVLFDELSVTENIFVGQYLHTGLLKKLDWP
AMHRKASEILTRLEVQIDPRATLKTLSIAQRHMVAIARALSFEAQVVILDEPTAALSQHE
ILEFYQIVERLKQDGKAILFISHKFDEIFELADYYTILRDGVYVSSGAINDITEERMVAM
MVGRAITQTYPKVDCIPGETVLEVKDLCHPTEFAHISFSLRKGEILGFYGLVGAGRTELM
QALSGVSHPSSGDIVLKGKPMRFRQPADAISAGIVCVPEERQKQGAIIALPIAQNISLPQ
LSKLNPGGVLNDAREWRLADEYASRLQVKAFSWRQAVETLSGGNQQKVVIGKWLATHPEV
IILDEPTKGIDIGSKAAVHQFMSELVSQGLAVIMVSSELPEVMGMADRIIVMHEGLMVAE
YRAGEATAETIVSAASGIGQEAA