Protein Info for BWI76_RS00475 in Klebsiella michiganensis M5al

Annotation: sulfurtransferase FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 34 to 276 (243 residues), 311.9 bits, E=1.3e-97
• PF02634: FdhD-NarQ
  • amino acids 38 to 275 (238 residues), 234.9 bits, E=5.6e-74

Best Hits

Swiss-Prot: 90% identical to FDHD_KLEP3: Sulfur carrier protein FdhD (fdhD) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K02379, FdhD protein (inferred from 90% identity to kva:Kvar_5031)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See A0A285AVL9 at UniProt or InterPro

Protein Sequence (278 amino acids)

>BWI76_RS00475 sulfurtransferase FdhD (Klebsiella michiganensis M5al)
MNKKPLEQIENVTDITGYRQVSLWKRQNLQHPQPDELAEEVPVALVYNGISHVVMMATPK
DLAQFAVGFSLSEGIIENRGEIYGMDVLQACNGLEVQIELSSRRFMGLKERRRALAGRTG
CGVCGVEQLNDIGKPVQPLPFTQTFDLANLDRALAHLHDFQPIGRLTGCTHAAAWVRPSG
DLAGGHEDVGRHVALDKLLGHRAESEGAWQNGAALVSSRASYEMVQKAAMCGVEILFAVS
AATTLAVDVAERCNLTLVGFCKPGRATVYTHPQRLIAG