Protein Info for BWI76_RS00095 in Klebsiella michiganensis M5al

Annotation: DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00126: HTH_1" amino acids 10 to 66 (57 residues), 48.3 bits, see alignment E=8e-17 PF03466: LysR_substrate" amino acids 101 to 313 (213 residues), 44.8 bits, see alignment E=1e-15

Best Hits

Swiss-Prot: 77% identical to YIDZ_CITK8: HTH-type transcriptional regulator YidZ (yidZ) from Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

KEGG orthology group: None (inferred from 92% identity to eae:EAE_07070)

Predicted SEED Role

"Putative LysR-family transcriptional regulator YidZ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AVB4 at UniProt or InterPro

Protein Sequence (319 amino acids)

>BWI76_RS00095 DNA-binding transcriptional regulator (Klebsiella michiganensis M5al)
MKKPLSSLDLNLLLCLQLLTQELSVTRTAKRMNVSPSAVSKSLAKLRAWFDDPLFVKTPL
GLSPTPLMSSMEQDLADWMQMGNQILDKPHHTMPSGLKFELAAESPLLMILLNSLSQRIY
QRYPQALIRLRNWDYDSLDAIIRGEVDIGFCGRETHPRSREQLSLLPWYIDFEILFTDLP
QVWLRADHPALNDEWSLDAFLRYPHINICWEQSDTWALDDVLHDLGHKRTVALTVPGFEQ
SLFMAAQPHHTMLATAPRYCQRYNQQHHLPLVSLPLPLEPSQLEKIRVPFTLLWHKRNSY
NPKIVWLRETLRQLYTEPL