Protein Info for BPHYT_RS36600 in Burkholderia phytofirmans PsJN

Annotation: lytic transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01464: SLT" amino acids 23 to 119 (97 residues), 63 bits, see alignment E=2e-21 PF18896: SLT_3" amino acids 38 to 112 (75 residues), 32.4 bits, see alignment E=1e-11

Best Hits

Swiss-Prot: 45% identical to IAGB_SALTI: Invasion protein IagB (iagB) from Salmonella typhi

KEGG orthology group: None (inferred from 58% identity to rpi:Rpic_1531)

Predicted SEED Role

"Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (149 amino acids)

>BPHYT_RS36600 lytic transglycosylase (Burkholderia phytofirmans PsJN)
MSAARRAAALFLFACVATARADCLDDAARYWNIPPDLARSIAMQESSMRPGVVTKNQNGS
RDIGLMQINSSWLPTLRRYGIHEADLLDGCKNAYVGNWILASNIQRLGFNWDAIGAYNAK
SPDKRDVYARKIYRQLLAVQAGKASLLNR