Protein Info for BPHYT_RS35720 in Burkholderia phytofirmans PsJN

Annotation: phosphopantetheinyl transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 PF01648: ACPS" amino acids 118 to 221 (104 residues), 59.2 bits, see alignment E=1.9e-20

Best Hits

KEGG orthology group: K06133, 4'-phosphopantetheinyl transferase [EC: 2.7.8.-] (inferred from 100% identity to bpy:Bphyt_7218)

Predicted SEED Role

"4'-phosphopantetheinyl transferase (EC 2.7.8.-)" in subsystem Fatty Acid Biosynthesis FASII (EC 2.7.8.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TAK1 at UniProt or InterPro

Protein Sequence (231 amino acids)

>BPHYT_RS35720 phosphopantetheinyl transferase (Burkholderia phytofirmans PsJN)
MYSIDPVPLSHDGPSDIALWRIDIDFTASLDAPAFVSLSDDERTRARNFRRHEDALRFVS
VRAALREELARRLDIAAHAMRFAPDANHRPHLADSDRFDFNVSHAGAHGLIAMSAVRRVG
VDIEQCSDKFDWRSIAALTLDQEETAWIERLDAAQRSAAFYDAWVAKEALVKTTGVGITR
GLQHLTVLPREGARVTLRKQIPADMRDVAAYWLAAPDAYAACVAWSVTPFR