Protein Info for BPHYT_RS35375 in Burkholderia phytofirmans PsJN

Annotation: aldehyde oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 746 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF20256: MoCoBD_2" amino acids 54 to 202 (149 residues), 47.2 bits, see alignment E=2.2e-16 amino acids 608 to 689 (82 residues), 47.4 bits, see alignment E=2e-16 PF02738: MoCoBD_1" amino acids 330 to 570 (241 residues), 117.3 bits, see alignment E=6.1e-38

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 100% identity to bpy:Bphyt_7146)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TAD1 at UniProt or InterPro

Protein Sequence (746 amino acids)

>BPHYT_RS35375 aldehyde oxidase (Burkholderia phytofirmans PsJN)
MFASARGAARRRFIKQSSALLASGLAIGFQLPEAFAKGDDKSGDPNPQAGEFEPNAWVRV
LPDDTIKLVVHKHDSGTGTRTALAAMVAEELDVDLFRVDVITPENPFYGDYIHPLWKVFS
TGGSTSVSLEYERLRRAGATARAMLIAAAAKQWNVAPSTCSTDNGFVVNKANGMRANYGS
LAQVAAQMPAPKDVVLKDPSQFKYIGKLRKKRGAVEKARGAFPYSIDVSLPDMLVAVVTR
APVIDARVRSVDAKAALAVPGVRQVLQIPGRPDILGGNQAGVAVLADDYWSAHKGQAALH
VEWEDSPLETFDSSTLAARQAMWLDDPAARVVPTIQSGDLKTAFPHGARVIEASYSMPYK
AQCPLEPINVTAWARKDGSIEYWGGLQVPSTVQEAAEVIGGIPANRVVLHELVSGGSFGS
RESKYWLFEVTWLALKVGKPVKLMNSREDEMRALYYHSASFHRAKAALDSRGNLATLQLR
AVMPASPEQWEPGYFDRPDRMDYSTTEAISKYEFAYGAPHVDIGWVRHETGVPTGWYRAV
SYIPNVFAVESFMDEAAHAGGRDPVEFRLTHMKDPRHQAVLREAAKRAGWGNALPAGTAL
GVATNQAYSSYVAVVARVARKGDGVVIEKLTCVADCGLAVSPGGVEEQLYGGLMWGLGHA
TVDRVDIRHGQIRQKNFDSYRVMRMSDLPEVDILIVQGDTSKPGGVGELSSPSVAPAVGN
AVFRLTGKRMRETPFELVKMGAKAKA