Protein Info for BPHYT_RS35335 in Burkholderia phytofirmans PsJN

Annotation: cobalamin biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 PF02492: cobW" amino acids 15 to 199 (185 residues), 191.4 bits, see alignment E=1.1e-60 PF07683: CobW_C" amino acids 261 to 354 (94 residues), 85.2 bits, see alignment E=2.3e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_7138)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TAB9 at UniProt or InterPro

Protein Sequence (360 amino acids)

>BPHYT_RS35335 cobalamin biosynthesis protein (Burkholderia phytofirmans PsJN)
MNHIHTTHNEIEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLV
LESTEEIYEMTNGCVCCVGAVREDLVRIVRMLVERPDRLDHIIVETSGLADPYPVAQTFF
LDDPIAKQVTLDAVVTMVDAKHIAAHLDDLVLDGSDNQAVDQIVCADRIVINKVDLVGPD
DIASLTQRIRGLNATAEIVESSYAQIDLGKILGVGANEFSQILVETDGLHEEEHAHGHEE
HEHEHAHHDDDHADHQHDESVSSVGIEVDADIDLDALQAWLAELRNSDAANLFRMKGILA
VQGQSHRYVLQGVHNVIELRAAQVWGSEPRSCRIVFIGRDLDRAALTDRFHACLAVPVAA