Protein Info for BPHYT_RS34775 in Burkholderia phytofirmans PsJN

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 PF00989: PAS" amino acids 12 to 59 (48 residues), 29 bits, see alignment 1.4e-10 TIGR00229: PAS domain S-box protein" amino acids 12 to 73 (62 residues), 23.8 bits, see alignment E=4.1e-09 PF08448: PAS_4" amino acids 14 to 130 (117 residues), 27.1 bits, see alignment E=6.5e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 146 to 309 (164 residues), 174.7 bits, see alignment E=1.3e-55 PF00990: GGDEF" amino acids 150 to 307 (158 residues), 151.6 bits, see alignment E=2.6e-48

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_7026)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7Z8 at UniProt or InterPro

Protein Sequence (312 amino acids)

>BPHYT_RS34775 diguanylate cyclase (Burkholderia phytofirmans PsJN)
MNVPVDSLSDLVVERVGFGIFVLDRDMNVLMWNRFMQDHSGLTPDQVVGRSLYTHFPELP
RVWLSRKIESVFQLGSFAFSSWEQRPYLFKFDHDRPITGGVDFMQQDCTFMPLMREREVV
AVCVTISDVTHVSIVQREREEAVAKLQEYADRDGLTGIANRRFFEARLRDEYTRWQRYGG
DMSVLLFDLDHFKKINDQFGHGVGDTVLRVMAQRVAEVVRAQDTFGRFGGEEFALLLPCT
PLEDAMRVAEKIRCTIADTPVEVQGTCVPVTASVGGASARVGVPSYDVLINEADAALYSA
KRQGRNRSVAFV