Protein Info for BPHYT_RS34510 in Burkholderia phytofirmans PsJN

Annotation: sodium:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 31 to 51 (21 residues), see Phobius details amino acids 57 to 75 (19 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 112 to 135 (24 residues), see Phobius details amino acids 155 to 176 (22 residues), see Phobius details amino acids 185 to 206 (22 residues), see Phobius details amino acids 213 to 230 (18 residues), see Phobius details amino acids 236 to 254 (19 residues), see Phobius details amino acids 266 to 288 (23 residues), see Phobius details amino acids 304 to 329 (26 residues), see Phobius details amino acids 350 to 369 (20 residues), see Phobius details amino acids 379 to 404 (26 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 10 to 405 (396 residues), 193 bits, see alignment E=3.8e-61 TIGR00831: Na+/H+ antiporter" amino acids 12 to 523 (512 residues), 310.6 bits, see alignment E=9.4e-97

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 100% identity to bpy:Bphyt_6974)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TA10 at UniProt or InterPro

Protein Sequence (528 amino acids)

>BPHYT_RS34510 sodium:proton antiporter (Burkholderia phytofirmans PsJN)
MSSVMGFKVVLLSLVAIIGLELLAKRLRLPPAAALLVGGAAMAFVPGLPRFNLDPELVLI
VFLPPLLMDGAYFSVWDEFKNNLGGILLLAIGAVAFTTLTVGLVVHWVVPALPWGACFAL
GAIVSPPDAVAAKAVLERVALPRRLMVLLEGESLLNDAAGLVLFRFAVAAALTGTFSAQH
AAGRFAVLALGGVAVGVTIGFVVVKLLRYLHDGYLIITAATLSAWISYIAGDTLDVSGVI
ATVSCGMVLGWHQHEVFSAAVRMRGTAFWQVVIFLMEALVFILIGLSLRGVMVRLGGFGD
ALTAFGPAVGAVLAVVVLSRFVWVFAVEWLKALVCKMTGRAGGTPDWRSATVTSWAGMRG
VVTLAIALSLPETMPGRDLILVASFAVILVTVLGQGTTIGPLIRWINPDHASERNQQHLT
EPQAWARLEAAQLAAIQPLVHGPDGSVIHPRLLEQYSYRARMTEAHQDEAAFPAKERAAH
YDVVLAAVSAARAELLHLHRTGLLHDKLLTVLEHDLDLQEIAAMHGRG