Protein Info for BPHYT_RS34440 in Burkholderia phytofirmans PsJN

Annotation: serine--glyoxylate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K00830, alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC: 2.6.1.44 2.6.1.45 2.6.1.51] (inferred from 100% identity to bpy:Bphyt_6959)

Predicted SEED Role

"Serine--glyoxylate aminotransferase (EC 2.6.1.45)" in subsystem Photorespiration (oxidative C2 cycle) or Serine-glyoxylate cycle (EC 2.6.1.45)

MetaCyc Pathways

glycine biosynthesis III (1/1 steps found)
L-serine biosynthesis II (3/4 steps found)
formaldehyde assimilation I (serine pathway) (9/13 steps found)
photorespiration I (6/9 steps found)
photorespiration III (6/9 steps found)
photorespiration II (6/10 steps found)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.51

Use Curated BLAST to search for 2.6.1.44 or 2.6.1.45 or 2.6.1.51

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T9Z6 at UniProt or InterPro

Protein Sequence (406 amino acids)

>BPHYT_RS34440 serine--glyoxylate aminotransferase (Burkholderia phytofirmans PsJN)
MLKLDFHPAGRHFLQIPGPSPVPDRILRAMSYPTIDHRGPEFGELGLKVLDGIKKIFKTQ
QPVVIYPASGTGAWEAALSNTLSPGDHVLMFETGHFATLWQKMAESLGLKPEFLGLPGIE
GWRRGVQPQMIEERLRADTQHAIKAVCVVHNETSTGVTSDIAAVRRAIDAAGHPALLLVD
TISGLACADYRHDEWGVDVTVSGSQKGLMLPPGISFNAISPKAVAASKQARLPRSFWDWT
DIVEMNKTGYWPYTPNTNLLYGLNEALEMILGEGLDNVFARHERLAEATRRAVRAWGLEI
QCADPSVYSPVLTGVMMPDGIDADAVRKLIYERFDMSLGTGLGKMKGRMFRIGHLGDCND
LMLLATLAGCEMGLRLAGVPLKESGLPAAMEWLSQPTKASGLKAAA