Protein Info for BPHYT_RS34355 in Burkholderia phytofirmans PsJN

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1169 transmembrane" amino acids 29 to 53 (25 residues), see Phobius details amino acids 331 to 350 (20 residues), see Phobius details amino acids 357 to 382 (26 residues), see Phobius details PF00512: HisKA" amino acids 559 to 624 (66 residues), 61.3 bits, see alignment 1.1e-20 PF02518: HATPase_c" amino acids 671 to 786 (116 residues), 92.5 bits, see alignment E=3.5e-30 PF00072: Response_reg" amino acids 939 to 1048 (110 residues), 78.3 bits, see alignment E=7.7e-26

Best Hits

KEGG orthology group: K07677, two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC: 2.7.13.3] (inferred from 100% identity to bpy:Bphyt_6941)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T9Y1 at UniProt or InterPro

Protein Sequence (1169 amino acids)

>BPHYT_RS34355 histidine kinase (Burkholderia phytofirmans PsJN)
MQKILDRTQESLAQAFATLAQSAKRQQRLYLVTIGSLMLIVLIFALVLIVVAGLKQLDYR
RALASQNATDISLLIHQEESFLRRAALTLDYYYGPSGGRSAPDDVQQAILKTGVALGKTD
GADSNFDIVVGEITRNAWGSQLGERLGRLYEAAQSTLVTQQAFEIQQRATLIGLNEDYAA
ILPSLTHPLAGQTSALDQAAMPAPQPAIASLLRETLERRIEAQTGRRVPRKGERIWLEPY
RDPLLNRLVISVVGAYYDGDTPTVLISTSFPLDALALRLAPPDNEGVNLLMTVDRRIAVS
SMPLDASVTNLVQRAVAATPSQIFHYGREGVIFHEPLALGFGLLVGYVPWRALAVALGWQ
LAVIGCLTALILMTIALMARYFGLRLLRNSFAETSRALQSEMLNHVLVSATPVGLCIVRQ
SDYSVLTTNALAIELLGIEADSNRLPPHIVGEFLAQAPVQPSAMSFARVAAFVVPARPAR
MPAQSVQQSPTEQRNEAQLSPSPDQDGGAPSQFLQFIYAPARYAGENVLFCAILDVTAQT
VLEQQLRHAQQTSEALMRARTNFFAAMSHEIRTPLNALLGNLELFARTPGLEAHSQRLAT
LDLAADALRRVVNDILDFSKIDAGEMLLVREPFLLIDVFENIALSYAPMHGERSIRFYAL
LSPTLDQTLIGDRMRISQIVNNLLSNAFKFTSTGKITLRAEVTDDSPDRAMLTIRVSDSG
AGMNEETLARLFKPFAQGELGASHGAGGTGLGLAICARLCELMGGHIVAESVPSVGSAFR
ISIPLAKPPVDSRAPAKARKQRGIVLVLSMEREAGEIMEHWLHHAGWAGHLVTLPDAAQA
WLRLNRADAVVVSGEYGLDVIAALRALQPVGVVWITRAGPLHPEARGEGVLEVTEFSRTA
VQSAIELAHETKSTTAVPTAARSESGPAGIHPTLRGLPVLVAEDNPLIQNLIAEQLVELG
CVPTIAHDGEHALKLFEETPFELVLTDIHMPEMDGYQLLAALRKLQATVRVLAFSAVAEH
EEAHNWRERGFSGYVAKPASLRELQAALLEAAPQSVATAEPMSSAAAGSALSTDDKARYT
AMLKQHLQKDLPRLLAIVEEEDVQALAGWAHSASGAFVVVQEPRFVEQCRRLQRLCNDEG
RWTTEMDEISISLHEALSDHYGLDEQSAH