Protein Info for BPHYT_RS34075 in Burkholderia phytofirmans PsJN

Annotation: chemotaxis protein CheY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 PF00072: Response_reg" amino acids 4 to 113 (110 residues), 76.4 bits, see alignment E=1.9e-25 PF00196: GerE" amino acids 150 to 204 (55 residues), 75.1 bits, see alignment E=2.6e-25

Best Hits

Swiss-Prot: 45% identical to BVGA_BORPA: Virulence factors putative positive transcription regulator BvgA (bvgA) from Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)

KEGG orthology group: K07690, two-component system, NarL family, response regulator EvgA (inferred from 100% identity to bpy:Bphyt_6883)

Predicted SEED Role

"DNA-binding response regulator, LuxR family, near polyamine transporter" in subsystem Polyamine Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T9S3 at UniProt or InterPro

Protein Sequence (213 amino acids)

>BPHYT_RS34075 chemotaxis protein CheY (Burkholderia phytofirmans PsJN)
MSTILVIDDHPAFRMVIKMQLVQLLGVEEVIEADNGQTAVELARIHAPELAILDLDIPRI
SGLDVIPRLKLAHPQIRVMVLSGHDPATFAPRAMRSGVHGFVGKSQEMKEIMRGVEAVMA
GYTVFPMAVGGAGMTFADGVGGEEARIGLLSDKELVILQMLSKGMSNKAIGDALFISNKT
VSSHKTRIMHKLGVKSLVELIDLARRCRIASTQ