Protein Info for BPHYT_RS33700 in Burkholderia phytofirmans PsJN

Annotation: ModE family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF00126: HTH_1" amino acids 34 to 93 (60 residues), 33.8 bits, see alignment E=2.7e-12 TIGR00638: molybdenum-pterin binding domain" amino acids 134 to 202 (69 residues), 71.6 bits, see alignment E=2.2e-24 amino acids 209 to 276 (68 residues), 71 bits, see alignment E=3.3e-24 PF03459: TOBE" amino acids 136 to 198 (63 residues), 60.3 bits, see alignment E=1.8e-20 amino acids 212 to 274 (63 residues), 48.7 bits, see alignment E=7.2e-17

Best Hits

KEGG orthology group: K02019, molybdate transport system regulatory protein (inferred from 100% identity to bpy:Bphyt_6807)

Predicted SEED Role

"DNA-binding domain of ModE / Molybdate-binding domain of ModE" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T9J9 at UniProt or InterPro

Protein Sequence (278 amino acids)

>BPHYT_RS33700 ModE family transcriptional regulator (Burkholderia phytofirmans PsJN)
MTSDRTDPSLETLELGGSVWFQAGAQTLGGASRIALLEAIGETGSITSAAKEVGISYKGA
WDAVDTMNNLAGEPLVVRLTGGKGGGGTTLTPRAVKLIETFRAVEREHRRFLERAGAAIE
GFATDWDLIGRIGVKTSARNQLYGTVSAITRGAVNDEIALTLPGGHAIVSVITHESTETL
GLAEGAAAFALIKASWVVLLVDNASGTPLKLSARNQLRGTVQSVKRGAVNAEVSLMLHGG
AVITAVVTHGSLDTLGLVEGGSAVAAFKASSVILGVKD