Protein Info for BPHYT_RS33430 in Burkholderia phytofirmans PsJN

Annotation: dimethylmenaquinone methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 999 PF01565: FAD_binding_4" amino acids 77 to 213 (137 residues), 119.1 bits, see alignment E=3.1e-38 PF02913: FAD-oxidase_C" amino acids 302 to 554 (253 residues), 170.8 bits, see alignment E=1.1e-53 PF13183: Fer4_8" amino acids 592 to 669 (78 residues), 34.8 bits, see alignment 4.9e-12 PF13534: Fer4_17" amino acids 595 to 670 (76 residues), 27.9 bits, see alignment 7e-10 PF02754: CCG" amino acids 776 to 849 (74 residues), 15.9 bits, see alignment 3e-06

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 100% identity to bpy:Bphyt_6755)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.14

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T9E7 at UniProt or InterPro

Protein Sequence (999 amino acids)

>BPHYT_RS33430 dimethylmenaquinone methyltransferase (Burkholderia phytofirmans PsJN)
MGTSFDEQQGAGVDELHDNGTSALKRAPHVATPFTGTAAVMQALEADLRSHVRGEVRFDQ
GSKALYAADASNYRQVPLAVVVPADVDDLLATLAACRRNDVPFLPRGGGTSQNGQCVNVA
VVADASKYVNRVVSVDPVARVAIVEPGVVCDTLRDAAEQHGLTFAPDPATHSRCTLGGMI
ANNSCGAHSVMAGKTVENVEALEIATFDGARFWVGPTSDQELEHIIAAGGRQGEIYAALK
QLRDTYAEQIRARFPQIKRRVSGFNLDQLLPENGFNVARALVGTEGTCALTLQAKVRLVK
SPAMRVIVVVGFTDIYTAADAVPHFMRCEPIAVEGLDRAIIRGLQARGLKKDEIALLPEG
DAWVVLEFGADTQDDVMLKARAAAACFASGEAGPNVSAMLVEDRALQAKVWSIRETGASA
VALSVDSGTPDPVVGWEDAAVDPLRLGDYLRAFQALVDRYGYETSLYGHFGDGCVHARIT
FDLRSAEGVATWRKFLREAAELVVEFGGSLSGEHGDGQAKAEFLPIMYGPELMQAMEQFK
AIWDPANRLNPGKVVHAYRADENLRMGPAYKPVTLQTRLTFASQEGEGFQREIERCIGMG
KCRSLEGGTMCPSYRATREEKYSTRGRAHLFWEMLQGDVIADGWQSREVKEALDTCLACK
GCKSDCPTHTDMASYKAEFLSHYYETNRRPRQALFMGRIGEWAPWAARFPRLTNFMTSAP
CLSSFGKWLAGVAQTRELPRFADATYRQIARRSPQSARDARGDVKKVILWVDTFNDHFTP
EIAQAAADVLKQLGWHVVLPKNRLCCGRPLYDFGLLERARELLTHILDDLADDIAAGVPL
VGLEPGCLSVFKDELLKQLPNHALAKKLSAQTFLFSDFVARQSFDWPTLAADVIVHGHCH
QKALFGMQGDTALLNKLGVKWKLLDTGCCGMAGSFGFNAEHHALSTKIGEDKLFPAVRAA
SVETIVLTNGFSCREQIEQGTGRHAMHIAQLAQRALAAR