Protein Info for BPHYT_RS32770 in Burkholderia phytofirmans PsJN

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 PF00512: HisKA" amino acids 195 to 256 (62 residues), 35.8 bits, see alignment E=9.9e-13 PF02518: HATPase_c" amino acids 301 to 416 (116 residues), 78.2 bits, see alignment E=1e-25 PF00072: Response_reg" amino acids 439 to 546 (108 residues), 72.4 bits, see alignment E=5e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_6621)

Predicted SEED Role

"Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T917 at UniProt or InterPro

Protein Sequence (552 amino acids)

>BPHYT_RS32770 histidine kinase (Burkholderia phytofirmans PsJN)
MEQRVLILAPFGRDADVIAEVLHKDKRLCVACRDADTLTAALDAGAGSALIAEEALAGNH
AARLFDWLEQQPAWSDFPFILLAASRLGHRSERGLEVLERLGNVVVLERPLNSETLRRAV
ASSLRARARQYESRRHLAERIEAQEALVQLNDSLESRIAERTQELASANNRLMMEIHERA
KVQAVLVQSQKMEALGQLTGGIAHDFNNLLNVIMVNAELIARVSSDERLRGMAATVKRAT
QRGAKLTGQLLTFSRNSNLDLKAVDVVALLQGMRDIITVSLGSSIRYTNEFDGDEMWTQA
DANQLELAILNLAINARDAMPGGGQLGIRVRQREAPDQTLAEGRYVVVEVADTGSGVPPD
VVSRVFDPFFTTKPIGKGTGLGLSQVYGIARQAGGTARLFSEEGVGTTVELWLPLRERVA
PQAEAASDAEANVVGEKRVLVVEDDSEVRAMLVESLRMLGYTVTEAADGRTGLNRLQDDN
PDLLMVDFAMPGMNGIDVIAEARKMREDLPVILATGYADVDISGLAVKRCTILRKPFQLD
DLARTVRLGLAA