Protein Info for BPHYT_RS31635 in Burkholderia phytofirmans PsJN

Annotation: choline dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 PF00732: GMC_oxred_N" amino acids 108 to 328 (221 residues), 74.2 bits, see alignment E=1.4e-24 PF05199: GMC_oxred_C" amino acids 417 to 533 (117 residues), 102.4 bits, see alignment E=3.1e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_6389)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T8P2 at UniProt or InterPro

Protein Sequence (547 amino acids)

>BPHYT_RS31635 choline dehydrogenase (Burkholderia phytofirmans PsJN)
MLDEAQHHPRGKNGRAPDVFERGGWVPMREYPNDEEVDFAIVGTGAGGGTLACRLAEQGF
KVVAFDAGAWWRPLEEFASDESHQAKLYWTDERICDGENPLKLGNNNSGKAVGGSTVHFA
MVSLRFRPEWFRSRSVLGYGADWPLDWREMWRYYAQVEDALKISGPVNYPWGPKRPRYPH
RAHELNAAALVLARGAEALGIDWTATPLATLSAPRGKAHPCVYRGFCTSGCATNAKQSAL
VTWIPRAVSAGAEIRDLAMVGRIATNDAGLATGVEYRREGRWQFQRAKHVVVAGYAIETP
RLLLMSANGRFPQGLANSSGLVGKNLMAQSNQAVYGTFDEEIRWYKGPPSLAITEHWNYK
DTGKDFFGGYCYMSQGPLPAGWASVQNGRGLWGDALAGEMHKYNHQAGLKIVGETLPQER
NRVTLADEKDQYGLPVARVTYSLCDNDKRLIAHSLDFMEQAIRAAGGNEIWRENDDTCHL
NGTARMGDDPSTSVVNADCRSWDIPNLWVCDGSVFPTVGGVNPSLTIQAIACRTAERIAA
LAARGEL