Protein Info for BPHYT_RS30945 in Burkholderia phytofirmans PsJN

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF00356: LacI" amino acids 2 to 46 (45 residues), 57.8 bits, see alignment 1.5e-19 PF00532: Peripla_BP_1" amino acids 60 to 307 (248 residues), 84 bits, see alignment E=2.7e-27 PF13407: Peripla_BP_4" amino acids 61 to 310 (250 residues), 35.7 bits, see alignment E=1.4e-12 PF13377: Peripla_BP_3" amino acids 167 to 328 (162 residues), 119.3 bits, see alignment E=3.8e-38

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to bpy:Bphyt_6244)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TAX5 at UniProt or InterPro

Protein Sequence (333 amino acids)

>BPHYT_RS30945 LacI family transcriptional regulator (Burkholderia phytofirmans PsJN)
MLSDVAKLAGVSTATVSRVYNEPDKVSANVRERVEHAALTLNWFPNAAGRALASTRSHIA
GIIIPTLDDRVFASQVSGMQAAFAARGITLVLGCSNYDPAQALTQVRAMLARGVEAMAVV
GEAHPAELFDALRLYRVPYAVTYAYRKDSPHTCIGFDNHAAYAEITEHLIGLGHRAFAVC
IQPTRDNDRVQARVAGIRATLERHGLAVRPEHMFEGESTMGFGRRSLRTIWQASGERPTA
IICGNDHIALGVLREAEELGIAIPGELSVTGFDDLEMAQEIRPALTTMRVDTYEIGQLAA
QYLLDTLDGKRPLHGHEVHALFQLRQSTGPAAR