Protein Info for BPHYT_RS29890 in Burkholderia phytofirmans PsJN

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 231 to 249 (19 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details PF00126: HTH_1" amino acids 8 to 66 (59 residues), 81.9 bits, see alignment E=2.6e-27 PF03466: LysR_substrate" amino acids 94 to 296 (203 residues), 172.9 bits, see alignment E=6e-55

Best Hits

Swiss-Prot: 50% identical to RBCR_ALLVI: RuBisCO operon transcriptional regulator (rbcR) from Allochromatium vinosum

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_6028)

Predicted SEED Role

"Cys regulon transcriptional activator CysB" in subsystem Cysteine Biosynthesis or DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T892 at UniProt or InterPro

Protein Sequence (315 amino acids)

>BPHYT_RS29890 LysR family transcriptional regulator (Burkholderia phytofirmans PsJN)
MTMRNATLRQLKVFETVARHLSFSRAAEELHLTQPAVSTQVRQLEEHAGLPLFEQLGKKI
YLTPAGTEMLHYSRAIIQQFHEVDEAMSQLKGVSGGKLNVAVISAGDYFFPRLLAEFTRR
YSGVVLNLAVHNREELLHQLATNQTDLAVMVRPPHETDATNEPFAPHPYVIVAAPTHPLA
NKRNIKFSQLANEAFIVRERGSDTWNSMEEGFAGRLANLKIAMEIKSTETIKQAVIAGMG
IAFLSAHTISLELQLGHLVVLDVESFPVMLNWYVVHRKNKRLPPVAVAFKRFLMEEGANL
IEKITRVKELSVYKQ