Protein Info for BPHYT_RS29510 in Burkholderia phytofirmans PsJN

Annotation: deoxyuridine 5`-triphosphate nucleotidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 325 to 346 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 408 to 567 (160 residues), 156.9 bits, see alignment E=2e-50 PF00990: GGDEF" amino acids 410 to 565 (156 residues), 164.3 bits, see alignment E=1e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5950)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T816 at UniProt or InterPro

Protein Sequence (604 amino acids)

>BPHYT_RS29510 deoxyuridine 5`-triphosphate nucleotidohydrolase (Burkholderia phytofirmans PsJN)
MIRPGLTFKLSVLLACIGVLASGATGYYAYRANRTMLVNEAERSLLMSTELLGQRFSTSI
DDVGADALVLASMPSTAEVAQTDDGAGPNAARERLAQVYSSFMVHHPEYLQVRLISRQHY
GLELVRFDRDADGLVRVEGDKLQEKGQFAYVFDTLTFSPGRIYTSPITVNHEYGSHAAQG
KPTLRLGTPVSNGNGAVVGVIVIDIDLAGLFRRVQSDLPSDYEVYLANEWGDFLVNPDAS
KTFGFDRGRRVLMQDSFSVTKPLFEQTQSEVLVNGLARPHQAAGQVLAFVRRPFGDLEGN
RFIVLGLAKPLDDVLSGANLLGDRIVRMVLIFSVLALFLAVLFARALTKPLHSLAYAATH
LFAEHAMETLPLKRTDEIGVLARCFDRLRREIKAQMDALHAKQRELVHLATHDVLTGLPN
RVLFMEKLENSIDEATRREEGLAVLFVDLDRFKQINDQFGHAVGDKVLVAVARRLKQVLC
SADVVARLGGDEFIVLIEGPRSAEAAPAIASRIMAALNEELQVDGQGMTVGASIGISQFP
DDSGTAEELLLNADAAMYAAKSGGRCAYMRYHDVLDMRRREQFEQAHAAAGIGATEGHEA
EPTA