Protein Info for BPHYT_RS29135 in Burkholderia phytofirmans PsJN

Annotation: acriflavin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1082 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 386 to 407 (22 residues), see Phobius details amino acids 431 to 453 (23 residues), see Phobius details amino acids 458 to 460 (3 residues), see Phobius details amino acids 464 to 488 (25 residues), see Phobius details amino acids 537 to 556 (20 residues), see Phobius details amino acids 880 to 900 (21 residues), see Phobius details amino acids 909 to 928 (20 residues), see Phobius details amino acids 934 to 958 (25 residues), see Phobius details amino acids 984 to 1003 (20 residues), see Phobius details amino acids 1015 to 1038 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 3 to 1039 (1037 residues), 656.8 bits, see alignment E=2.7e-201

Best Hits

KEGG orthology group: None (inferred from 61% identity to bcj:BCAS0582)

Predicted SEED Role

"Cation/multidrug efflux pump"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TFV5 at UniProt or InterPro

Protein Sequence (1082 amino acids)

>BPHYT_RS29135 acriflavin resistance protein (Burkholderia phytofirmans PsJN)
MWIVNVALKRPYTFIVMAILIVLATPFVLFTTPVDVLPEINIPVVSIIWTYTGLSAEDMA
NRITSVNERSLTTTVNDIEHIESQSLAGITILKVFLQPNANIQTAIAQTVAVEQAQLKQM
PPGATPPLVISYSASSIPVIQLGLSSPKLSEQALNDTALNFLRPQLVTIPGAAVPYPYGG
KSRLISVDLNTRALLAKGLTPSDVVSAFNAQNLILPTGTAKIGAKEYTIDMNGSPTTLEG
LNDIPVRTLNGATTYLREVAHVRDGFSPQTNIVRQDGHRGVLMSVLKNGSASTLSIVNTL
KGLMPNAQAALPPDLKITALFDQSVFVKAAVQGVVREALVAAALTAAMILLFLGNWRSTC
IIAISIPLSILSSLIALHALGQTINIMTLGGLALAVGILVDDATVTIENIERHLHMGTNL
HDAILDGAGEIAIPALVSTLCICIVFVPMFFLTGVARYLFVPLAEAVVFAMLASYILSRT
LVPTLAMLLMGHAHKPKPGAKPNLFMRLYHRFDRGFERMRAGYIMILSSLLVRRGRFGSV
FLGFCVVSMGLIFVLGEDFFPSVDAGDIRLHMRAPTGTRIEETARLADQVENVIREVVPH
KELGTILDNLGLPYSGINLSYSNAGTIGTLDGEIQVALNEDHKPTQIYMDKLRALLPQRF
PGVEFFFQPADIVTQILNFGLPAAVDVQISGANQEGNFDVARKLLKQVRMIPGTVDTHIQ
QKLDEPAINLQMDRTRLQQLNLSASNVAQNVLISLSGSSQTSPGFWFNNRNGVEYSVAVQ
TPQYQVSSIDELLRTPVSGAANGPTQLLGNLVRVSPKSQFAEVTHYNIRPVIDLYVSVEK
RDLGSVANQVDKLVDNVRASLPRGSQITVRGQVQTMRSSFFGLGLGVAMAIVLVYLLIVV
NFQSWVDPLIIVSALPAALAGIVWMLFLTGTHLSVPALTGAIMTMGVATANSILMVSFAR
QRLSAGAPPLTAALEAGASRIRPVLMTAFAMIIGMIPMALGLGEGAEQNAPLGRAVIGGL
LFATVSTLFFVPLVFAAIHSRLARRHRGDGDDGDDGDDGGANHTDSRGDGPAPEHGGAGK
PA