Protein Info for BPHYT_RS28910 in Burkholderia phytofirmans PsJN

Annotation: diguanylate phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 transmembrane" amino acids 29 to 47 (19 residues), see Phobius details amino acids 58 to 75 (18 residues), see Phobius details amino acids 82 to 104 (23 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 162 to 182 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 195 to 352 (158 residues), 138.3 bits, see alignment E=1e-44 PF00990: GGDEF" amino acids 199 to 349 (151 residues), 126.3 bits, see alignment E=1e-40 PF00563: EAL" amino acids 386 to 604 (219 residues), 135.1 bits, see alignment E=2.8e-43

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5831)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGJ1 at UniProt or InterPro

Protein Sequence (777 amino acids)

>BPHYT_RS28910 diguanylate phosphodiesterase (Burkholderia phytofirmans PsJN)
MLSTATQQPFDAGLRDRFHRRSLEHQRPLSTVTMAFTVVAFLCFVGARNLVDGPAAPLGY
RLTCALLLALLVLAIPRVRSTWSFGLIGVAYSQVLVAGLAMNIVGVTQPLLWTLPAMVVI
PICAAPLWLTPTHFVTGSVLFYATAFALLFGQPLTHDVETVVWMWIVAIGVPTSVVFHFG
FYRFRRNHFLLESQLAQLAATDPLTGLQNRRAFVKQAERRLDTVTPDTRTSAIFLDIDNF
KSLNDRFGHAIGDHALYQVAQVLMEEISADDSVSRIGGEEFALLLGDGLTGALHVAERLR
HAIAAIERPDGRLTASFGVAEHRSGESIMVLLDRADEALLRAKHSGRNRVRAERALPREA
LQLLADDGSDENGAPVRRHRWEEYYLTSYFQPLYSLSHQKQVGFEALLRGEQDDGTLVPP
AVLFAPRPSSDEGGLDRASHVVHLANARKSLPDDAWLFLNILPATFIAEGYADQLAKIVR
SVGLEPERVILEILESHGGSVDDMSRAAALYREHGFLIAVDDFGAGQSNLDRLLRIRPDL
VKLDGELIRATGHGTEQPILPKLVSLLHLAGMLVVVEGVETAEELILAVESNVDFAQGFL
LGRPAKEIAPPESVHRRIDEAFDVIAQGRAHQHALFETEVEPYRVALRLAADALLAGVAM
EEAFARLARFERCISCFILDDAGRQIGQEVQGPAWTTDGASLQPVANPRDARWDHRPYFR
NAVLLPGVAVSSNPYLSLASGRPCIAVTLALQFAAERSVIGVELDWSALGLPWPAAE