Protein Info for BPHYT_RS28870 in Burkholderia phytofirmans PsJN

Annotation: MarR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 135 TIGR02337: homoprotocatechuate degradation operon regulator, HpaR" amino acids 1 to 126 (126 residues), 135.6 bits, see alignment E=4.4e-44 PF12802: MarR_2" amino acids 21 to 80 (60 residues), 43.3 bits, see alignment E=5e-15 PF13463: HTH_27" amino acids 23 to 87 (65 residues), 30.8 bits, see alignment E=4.4e-11 PF01047: MarR" amino acids 23 to 81 (59 residues), 41.1 bits, see alignment E=2e-14

Best Hits

KEGG orthology group: None (inferred from 99% identity to bxe:Bxe_B2027)

Predicted SEED Role

"Homoprotocatechuate degradative operon repressor" in subsystem 4-Hydroxyphenylacetic acid catabolic pathway or Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGI7 at UniProt or InterPro

Protein Sequence (135 amino acids)

>BPHYT_RS28870 MarR family transcriptional regulator (Burkholderia phytofirmans PsJN)
MLLLRAREKMMERFRPLITAHGLTEQQWRVIRALNEHGPMEPRHISDICTISSPSMAGVL
ARMESMELVTKERFAEDQRRVLVSLTDTSAELVRVISKDLEAHYRELERKVGPEIVERVY
RAVDDLLAGLEEEEE